Late dinner and night time heartburn: scientific proof

If you had any doubts about whether eating early helps reducing nighttime heartburn look at this link with scientific article from Centre Hospitalier Universitaire Vaudois, Gastroentérologie, Lausanne, Switzerland.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1434162

Abstract: “This study examines whether eating food at different times has differential effects on intragastric pH. Experiments were done in 23 healthy volunteers (12 men). Intragastric acidity was monitored by ambulatory 22 hour pH-metry. Composition of meals was standardised: breakfast and lunch at 7 am and 12 noon respectively, and dinner at 6 or 9 pm, in random order. The time of going to bed and getting up was also standardised. With early dinner nocturnal pH was higher, than with late dinner (pH median: 1.67 and 1.39, p less than 0.001). During the remaining time periods, pH values were similar. Thus early dinner may be helpful in conditions where low intragastric acidity is desirable.”

It clearly proves that if you go to bed at 11pm and have later dinner at 9pm your pH will be 1.39. If you have early dinner at 6pm than your pH will be 1.69 or 20% lower.

Please note that the higher the pH the lower the acidity. Thus pH of 1 is very acid while pH of 5 is very alcaline.

Conclusion: moving your dinner 3 hours early will reduce your nighttime heartburn 20%… Of course your mileage may vary but trend is quite obvious.

Moving dinner even earlier won’t help much since you’ll get hungry by the time you need to get to sleep.

This study is also confirmed by many advices I get from the books and internet. Heartburn and eating late has a very close connection. Just dealing with late food cravings could make a significant difference in how heartburn affects your lifestyle.

Late dinner and night time heartburn: scientific proof

If you had any doubts about whether eating early helps reducing nighttime heartburn look at this link with scientific article from Centre Hospitalier Universitaire Vaudois, Gastroentérologie, Lausanne, Switzerland.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1434162
Abstract: “This study examines whether eating food at different times has differential effects on intragastric pH. Experiments were done in 23 healthy volunteers (12 men). Intragastric acidity was monitored by ambulatory 22 hour pH-metry. Composition of meals was standardised: breakfast and lunch at 7 am and 12 noon respectively, and dinner at 6 or 9 pm, in random order. The time of going to bed and getting up was also standardised. With early dinner nocturnal pH was higher, than with late dinner (pH median: 1.67 and 1.39, p less than 0.001). During the remaining time periods, pH values were similar. Thus early dinner may be helpful in conditions where low intragastric acidity is desirable.”
It clearly proves that if you go to bed at 11pm and have later dinner at 9pm your pH will be 1.39. If you have early dinner at 6pm than your pH will be 1.69 or 20% lower.
Please note that the higher the pH the lower the acidity. Thus pH of 1 is very acid while pH of 5 is very alcaline.
Conclusion: moving your dinner 3 hours early will reduce your nighttime heartburn 20%… Of course your mileage may vary but trend is quite obvious.
Moving dinner even earlier won’t help much since you’ll get hungry by the time you need to get to sleep.
This study is also confirmed by many advices I get from the books and internet. Heartburn and eating late has a very close connection. Just dealing with late food cravings could make a significant difference in how heartburn affects your lifestyle.

Onion, Garlic and heartburn

After series of experiments I discovered that fresh onion and garlic are guaranteed heartburn/stomach pain triggers for me. Even though both of them are not acidic in nature they contain very bitter substances which irritate my stomach and cause hell lot of pain. This pain is different from the usual heartburn caused by acid but it hurts as bad.

The only form of onion and garlic I can consume without any irritation is well cooked: fried or steamed. It is good that I can consume at least cooked onions since they add flavor to the food but cooking destroys many vitamins in onion thus making it less nutritious. But I haven’t discovered any way to make raw onions or garlic harmless for my stomach.

PS: Don’t believe to anyone who tells you that garlic or onion could help you against stomach diseases. They’re completely wrong.

Correction: actually it looks like onions don’t loose many vitamins and minerals during cooking. Please see tables below.

Cooked Onions
Serving size 1/2 cup, chopped (105g)

Amounts Per Serving % Daily Value
Calories 45
Calories from Fat 0
Total Fat 0g 0%
Sodium 0mg 0%
Cholesterol 0mg 0%
Total Carbohydrate 11g 4%
Dietary Fiber 1g 4%
Sugars 5g
Protein 1g
Vitamin A 0%
Vitamin C 10%
Calcium 2%
Iron
Raw Onions
Serving size 1/2 cup, chopped (80g)

Amounts Per Serving % Daily Value
Calories 35
Calories from Fat 0
Total Fat 0g 0%
Sodium 0mg 0%
Cholesterol 0mg 0%
Total Carbohydrate 8g 3%
Dietary Fiber 1g 4%
Sugars 3g
Protein 1g
Vitamin A 0%
Vitamin C 8%
Calcium 2%
Iron 0%

Onion, Garlic and heartburn

After series of experiments I discovered that fresh onion and garlic are guaranteed heartburn/stomach pain triggers for me. Even though both of them are not acidic in nature they contain very bitter substances which irritate my stomach and cause hell lot of pain. This pain is different from the usual heartburn caused by acid but it hurts as bad.
The only form of onion and garlic I can consume without any irritation is well cooked: fried or steamed. It is good that I can consume at least cooked onions since they add flavor to the food but cooking destroys many vitamins in onion thus making it less nutritious. But I haven’t discovered any way to make raw onions or garlic harmless for my stomach.
PS: Don’t believe to anyone who tells you that garlic or onion could help you against stomach diseases. They’re completely wrong.
Correction: actually it looks like onions don’t loose many vitamins and minerals during cooking. Please see tables below.

Cooked Onions
Serving size 1/2 cup, chopped  (105g) 

Amounts Per Serving % Daily Value
Calories 45
Calories from Fat 0
Total Fat 0g 0%
Sodium 0mg 0%
Cholesterol 0mg 0%
Total Carbohydrate 11g 4%
Dietary Fiber 1g 4%
Sugars 5g
Protein 1g
Vitamin A 0%
Vitamin C 10%
Calcium 2%
Iron
Raw Onions
Serving size 1/2 cup, chopped (80g) 

Amounts Per Serving % Daily Value
Calories 35
Calories from Fat 0
Total Fat 0g 0%
Sodium 0mg 0%
Cholesterol 0mg 0%
Total Carbohydrate 8g 3%
Dietary Fiber 1g 4%
Sugars 3g
Protein 1g
Vitamin A 0%
Vitamin C 8%
Calcium 2%
Iron 0%

 

Plavix and PPIs are bad combination

If you ask people who take PPIs about its safety the answer you most probably will hear: it is totally safe.

Well it looks like it is safe unless you combine it with Plavix. Recent research study found that in patients who suffered heart attack and were prescribed PPIs (in case of study it was Prilosec) together with blood thinner Plavix risk of repeat heart attack doubled in comparison with patients who were prescribed just Plavix. So Plavix+Prilosec equal to double risk of getting repeat heart attack.

It would be nice to get some study to figure out if Plavix+Prilosec are doubling chances of first heart attack. If it is so then it should be taken very seriously and every patient prescribed with PPIs should know what risk they may be taking.

Anyway looks like there are some hidden edges in PPI drugs. It doesn’t mean that we should stop taking them when heartburn is really bad but be careful and if you can find alternatives it maybe time to consider them.

Here you can find more details on this study http://www.healthfinder.gov/News/newsstory.aspx?docid=624675.

Plavix and PPIs are bad combination

If you ask people who take PPIs about its safety the answer you most probably will hear: it is totally safe.
Well it looks like it is safe unless you combine it with Plavix. Recent research study found that in patients who suffered heart attack and were prescribed PPIs (in case of study it was Prilosec) together with blood thinner Plavix risk of repeat heart attack doubled in comparison with patients who were prescribed just Plavix. So Plavix+Prilosec equal to double risk of getting repeat heart attack.
It would be nice to get some study to figure out if Plavix+Prilosec are doubling chances of first heart attack. If it is so then it should be taken very seriously and every patient prescribed with PPIs should know what risk they may be taking.
Anyway looks like there are some hidden edges in PPI drugs. It doesn’t mean that we should stop taking them when heartburn is really bad but be careful and if you can find alternatives it maybe time to consider them.
Here you can find more details on this studyhttp://www.healthfinder.gov/News/newsstory.aspx?docid=624675.