Dexilant Information

Although Dexilant is only available in prescription strength, it is one of the newer proton pump inhibitors for the treatment of acid reflux diseases such as GERD, gastroesophageal reflux disease. Because of its relatively late arrival on the market amidst a wealth of other such medications, many consumers are looking for Dexilant information before taking their prescription.

The following information is not meant to replace a diagnosis given by a medical professional nor is it intended to prescribe treatments. As a matter of fact, the sole purpose of providing Dexilant information is to help introduce this pharmaceutical which has only been on the market for about two years. Only a medical professional is qualified to treat any illnesses or conditions for which Dexilant is prescribed. Keep this in mind while reading what we have gathered to help you better understand this newer medication.

What Is Dexilant?

As mentioned, Dexilant is in a class of pharmaceuticals called proton pump inhibitors. They act by inhibiting the production of acid in the stomach – acid that causes acid reflux and other such conditions like GERD. If you think of the stomach as having literally millions of minute pumps that produce acid, you can liken Dexilant as a kind of control mechanism that turns those pumps off.

When Dexilant (Dexlansoprazole) was first released on the market in 2009, it was called Kapidex. Unfortunately, there were a number of instances when Kapidex was mistakenly dispersed interchangeably with other drugs having similar names. Among those pharmaceuticals were Casodex and Kadian which are drugs to treat totally different things. As a result, the developers and manufacturers of Kapidex applied to the FDA for a name change which was granted in March of 2010. Kapidex is now known as Dexilant but it is exactly, down to the last molecule, the same mediation.

One of the most innovative benefits of Dexilant as a proton pump inhibitor is that it is a dual acting delayed release capsule. Unlike other medications used to treat GERD, ARD (acid reflux disease) and erosive esophagitis, Dexilant goes to work immediately to reduce acid in the stomach with the fast acting granules within the capsule. Along with immediate relief, Dexilant contains granules of delayed release medication that go to work five hours (or later) after taking the dose. This serves a two-fold purpose: a) it immediately reduces acid and b) it inhibits the production of acid in the stomach up to 24 hours.

How Is Dexilant Taken?

Most proton pump inhibitors are taken once daily just about an hour before a meal. While Dexilant is also taken once daily, it can be taken irrespective of food intake. In other words, you can take it before, during or after meals. However, since it does have the quick release antacid feature, many people choose to take Dexilant before meals to avoid acid indigestion.

Like the other proton pump inhibitors, Dexilant capsules can be swallowed whole or they can be opened up to be mixed with a tablespoon or so of applesauce for those who have trouble swallowing pills or capsules. It is important to note that you cannot chew the granules as some are time released. You must swallow the applesauce down and follow by a glass of water if necessary – but do not bite down on the granules.

Potential Side Effects and Adverse Reactions

One thing to keep in mind when taking medications of any kind is that everyone has the potential to react differently to any given compound. While some people may have allergies to Dexilant and/or any of the ingredients in the compound, others may handle it quite well. With that being said, there are some ‘common’ side effects which have manifested in the greatest number of individuals who have reported adverse reactions.

Among the side effects which have been reported most frequently are nausea, diarrhea, vomiting, gas and stomach discomfort/pain. Also, some individuals have contracted upper respiratory infections as well, but this is not quite as common. There are, in addition to these side effects, the potential for more serious side effects which you should be aware of.

According to the manufacturer, there is always the possibility for an allergic reaction which would manifest in hives, rashes or swelling of the mouth, tongue and throat. Some people sensitive to Dexilant have experienced joint, muscle or bone pain while others became short of breath, dizzy, drowsy or generally weak. In some rare cases, chest pain and loss of consciousness were reported, but usually with inadvertent overdoses or as symptoms of severe allergic reactions.

There are several known medications which can either have adverse reactions when taken with Dexilant or can counteract the efficacy of one another. These medications usually fall into broad categories such as diuretics and anticoagulants. It is also known that ampicillin and Dexilant counteract each other.

Special Precautions When Taking Dexilant

Although not exactly a side effect or an adverse reaction, there are certain groups of people who should use extreme caution when taking Dexilant. If you are among these groups, make sure to talk to your doctor before taking Dexilant for the first time. The first group of people would be pregnant women, those who are trying to get pregnant and nursing mothers. After that, anyone with any conditions such as HIV/AIDS should likewise tell their physician they have the disease.

Elderly patients should also take Dexilant with extreme care as proton pump inhibitors are known to cause a weakening in the bones. As well, anyone who has osteoporosis or other bone disorders should use Dexilant with extreme care. Even so, since Dexilant is a prescription medication, it is always advisable to tell your doctor of any medications (prescription or OTC) that you are taking, along with any vitamins or health supplements that you may be using as part of your daily regimen.

Overdose and Emergency Procedures

While it is extremely rare to overdose if you take your medication only as prescribed, there may be times when you are experiencing extreme distress, perhaps causing you to forget whether or not you took your medication. In any case, if you feel that you have inadvertently taken an overdose of Dexilant, call your doctor or pharmacist immediately.

As with any other medication, use common sense. If you find someone unconscious, call 911. If you feel you are about to lose consciousness, call 911. The key to treating accidental overdoses is to act immediately. How you respond to an overdose is determined by the symptoms being presented. In any case, make sure to contact the appropriate professionals so that countermeasures can be taken.

Consumer Reviews

In compiling customer reviews gathered from around the web, we have found that Dexilant is meeting with a high amount of success. Almost 9 out of 10 reviews are highly favorable with very few individuals reporting that this medication was ineffective. A few consumers did have some adverse reactions such as nausea, diarrhea and skin rashes, but few said it didn’t work.

Actually, most users reported that the best part of Dexilant (above other proton pump inhibitors) is that it has both immediate and long lasting benefits. Those who suffer from acid reflux immediately after eating find that the quick acting compound in Dexilant provides relief while the delayed release granules continue working up to the full 24 hours as advertised. Dexilant has been well received by the majority of users.

Summary

Once again, it is important to note that this web site is not set up to be a substitute for proper medical diagnoses and treatments. This is an informative web site developed for those who suffer from all forms of heartburn and the acid reflux family of diseases. Because of this, we do not intend to ‘prescribe’ any medications which we review. Information is based on what is being written by the manufacturer, other medical reviewers and consumers taking the products.

It is our conclusion that Dexilant has benefits above and beyond other proton pump inhibitors. The most significant of these benefits is the fact that it has a quick acting component as well as a long lasting component. Other proton pump inhibitors cannot provide immediate relief for acid indigestion whereas Dexilant is able to do just that. Also, within the course of a 24 hour period it will continue to inhibit the production of stomach acid.

While we cannot prescribe medications, we can recommend or advise against them based on available information and consumer reviews. This is one of the medications which seems to have been well received and is doing the job it was intended to do. Therefore, if you have been diagnosed with GERD or any of the acid reflux diseases, you may want to ask your doctor if Dexilant is suitable for you. Never take this or any medication unless it has been prescribed to you.

Dexlansoprazole Information

While Dexlansoprazole is used to treat heartburn, it is not meant to be used for occasional heartburn. Rather, it is in a class of drugs known as proton pump inhibitors that work by reducing the amount of acid produced in the stomach. In other words, it is not a quick fix for heartburn resulting from eating too much or too much of the wrong foods.

What Is Dexlansoprazole?

Dexlansoprazole, as mentioned, is a proton pump inhibitor that can dramatically reduce the amount of acid the stomach produces. It is most often prescribed for the treatment of gastroesophageal reflux disease (GERD) and/or for the treatment of damage caused to the esophagus from acid reflux. This condition is usually referred to as erosive esophagitis.

In order to understand how Dexlansoprazole works, it is important to understand that there are literally millions of tiny little ‘pumps’ in your stomach which produce acid. Sometimes these pumps begin producing an overabundance of acid in order to attempt to digest food if you have eaten too much or too much of the wrong kinds of foods. Other times you are simply unfortunate enough to have faulty pumps.

Dexlansoprazole can provide relief up to 24 hours a day when taking the medication as directed because it works by inhibiting those pumps from producing so much acid. Again, keep in mind that Dexlansoprazole is not meant for the relief of occasional heartburn since it can take several days for the full effects to ‘kick in.’ It is most often prescribed for GERD and ARD, acid reflux disease. Clinical studies also indicate that Dexlansoprazole also helps to heal erosions in the esophagus and helps to keep acid reflux from returning.

How Is Dexlansoprazole Taken?

Whenever you are prescribed a new medication it is important that you follow the directions. Dexlansoprazole comes in a long acting, delayed release capsule that should be either swallowed whole or pulled open and taken in a bit of applesauce. It is imperative that you do not chew the little granules because, as mentioned, they are delayed release.

This medication is usually taken only once per day, at about the same time, and it may be taken before or after meals. It has been suggested that taking Dexlansoprazole about an hour before a meal will help to prevent acid reflux more effectively than if you take it after a meal. In any case, it is generally only taken once daily until the entire prescription is complete.

Potential Side Effects and Adverse Reactions

As with any pharmaceutical, there is always a chance of side effects or adverse reactions, especially if you are allergic to any of the ingredients in the compound. Even so, very few people have exhibited side effects when taken as directed and barring any allergies or contraindications based on other medications being taken during a course of Dexlansoprazole.

The most common side effects would be such things as nausea or gas, stomach discomfort or pain, vomiting and some people have gotten an upper respiratory tract infection. Severe side effects could include such things as:

  • rashes and hives
  • swelling of the mouth, tongue or throat
  • muscle, joint  or bone pain
  • chest pain
  • blistered or peeling skin
  • shortness of breath
  • dizziness, drowsiness, weakness, loss of consciousness

Keep in mind that these severe side effects are usually presented in people with an allergy to any of the chemicals in the compound and may also be presented in older adults (seniors).

Also, there is the potential for an adverse reaction if you are taking other medications which may include diuretics, Voriconazole, anticoagulants and ampicillin. In fact, you should always discuss any medications you are currently taking with your doctor prior to taking Dexlansoprazole for the first time. This includes herbal preparations, OTC pharmaceuticals and even vitamins and supplements.

Special Precautions When Taking Dexlansoprazole

Of course it should go without saying that you should only take Dexlansoprazole only as directed by your doctor/pharmacist and you should never take a prescription medication which has not been prescribed to you. Pregnant women, women who plan on becoming pregnant or lactating mothers should notify their doctor prior to taking Dexlansoprazole as should anyone who has osteoporosis or a family history of weak bones.

In fact, this is one of the reasons why older adults are often advised against taking proton pump inhibitors as they are already susceptible to weak bones that fracture easily. As well, anyone with any other medical conditions such as high or low blood pressure, low levels of magnesium or potassium in the blood or those who are HIV positive should also notify their doctor prior to taking Dexlansoprazole.

Symptoms of Overdose and Emergency Procedures

If you take your medication only as directed, you should not experience any of the symptoms associated with overdosing. However, things to watch for would be among the ‘severe reactions’ listed above. If you feel dizzy, disoriented or weak due to an accidental overdose, call your doctor immediately and if you cannot reach either your doctor or pharmacist it is possible to contact the National Poison Control Center Hotline at 1-800-222-1222. If you find a family member or friend unconscious the best course of action would be to call fire rescue at 911.

Important Information Regarding Dexlansoprazole

One of the biggest dangers which many people encounter is mistaking a heart attack for heartburn. The symptoms of a heart attack can, and often do, mimic heartburn which is why many people don’t get treatment on time. It is imperative to talk to a doctor if you are experiencing heartburn, especially that accompanied by chest pain, tingling in the arms or shortness of breath.

Also, it is important to understand that Dexlansoprazole is a proton pump inhibitor which is not meant to treat occasional heartburn. If you have a prescription for this medication and find that you are experiencing the above mentioned symptoms, it is not in your best interest to take another dose. Get to the doctor immediately as it may be your heart and not GERD or ARD!

Consumer Reviews

According to consumers who have taken Dexlansoprazole as intended, nine out of ten found the relief they were looking for. Most found that this particular proton pump inhibitor worked better than others they had tried in this class of drugs which included such popular medications as Prilosec, Nexium, Prevacid and Protonix.

Some users did report that upon further gastroscopes healing of erosions had begun in the esophagus and that they were finally free from many of the symptoms of acid reflux which they had been unable to find relief from with other medications in this class of drugs.

One of the most common benefits which many users reported was the fact that there is a dual action effect with Dexlansoprazole because some of the medication is released immediately into the system while some of the granules are delayed release.

There were a few consumers who found that they had some amount of allergic reactions to the medication and had to stop taking it. Most of those reactions included skin rashes, nausea, vomiting and diarrhea. A few people reported that although it helped acid reflux for the first week or two, the side effects began manifesting which made them unable to continue treatment.

Of the 36 reviews which were calculated into these statistics, the overall score was 8.4 out of 10 which is actually quite good. With 5 being the median, only a few reported anything lower than 4 with the only really bad scores coming from those who had allergies or adverse reactions due to other medications.

Summary

Before presenting our ‘take’ on this medication, it is important to realise that this site is informational only. We do not attempt to diagnose or treat any medical conditions and in no way attempt to replace proper medical advice. For this and any other medications it is always recommended that you seek counsel with your own physician prior to taking it for the first time. Of course, this should not be an issue as Dexlansoprazole is only available with a prescription and you should not take any medications not prescribed for you.

With that being said and based on what users are reporting, Dexlansoprazole is one of the newer proton pump inhibitors that has had overwhelmingly good results. Part of that success is due to the fact that this is one medication that provides both immediate as well as long acting results. While you cannot expect a proton pump inhibitor to act quickly, the other medication usually found in the long lasting brand name compounds does provide a modicum of immediate relief of acid indigestion.

Because of the fact that it can work quickly to provide a bit of relief as well as to inhibit acid production over time, Dexlansoprazole might be one of the better proton pump inhibitors on the market today. If you are currently taking other such medications and have found no relief, you may want to discuss this medication with your doctor.

Prilosec and Nexium do not increase risk of heart problems

According to recent review released by the Food and Drug Administration patients who suffer from heartburn are not at increased risk for heart problems as a result of taking Prilosec or Nexium. The FDA and its Canadian counterpart began reviewing the drugs, used by tens of millions of people, in May.

The drug’s manufacturer, AstraZeneca PLC, provided them with an early analysis of two small studies that suggested the possibility of a risk.

The agency said its review of that study as well as 14 others indicated no increased risk for patients.

“FDA recommends that health care providers continue to prescribe, and patients continue to use these products as prescribed,” the agency said.
Well it is a great news for us – heartburn sufferers. We can take our Protonixes, Prilosecs and Nexiums without worrying about consequences too much :) .

I hope they will do more research regarding all other concerns related to long term PPI treatment like malnutrition, potential lung diseases, etc. For example:

Vitamin B12 Levels During Prolonged Treatment With Proton Pump Inhibitors. 

Clinical Reviews

Journal of Clinical Gastroenterology. 30(1):29-33, January 2000.
Howden, Colin W.

Abstract:
Reduced serum vitamin B12 (cobalamin) levels have been documented occasionally during long-term treatment with a proton pump inhibitor (PPI) in selected groups of patients. This has largely been confined to patients being treated for Zollinger-Ellison syndrome who have sustained drug-induced achlorhydria, which does not ordinarily occur during treatment with a PPI. An appreciation of normal cobalamin metabolism and the pharmacological action of the PPIs adequately explain the mechanism for this reduction. PPIs do not promote the development of pernicious anemia.

 

Get your heartburn non-prescription medications on eBay

I always thought that the only way to get non-prescription heartburn drugs like prilosec, zantac or tums is to go to the nearest grocery or drug store. How big was my surprise when I found out that you can easily get them on eBay and for considerably cheaper prices!

Even though shipping might eat some money you still can be in a win situation and save some money.

 

Prilosec and Nexium don’t cause any heart problems

According to Food and Drug Administration study started in May Prilosec and Nexium don’t cause any heart problems.

Manufacturer AstroZeneca rised this concern when two small studies compared patients who underwent surgery with patients on a drug regimen. These studies found that patients on a drug regimen suffered from heart related issues more frequently than those with surgeries. It turned out that these studies were biased. Patients who underwent surgeries were significantly yonger when compared to ones who were treated with drugs. So higher rate of heart related issues could be easily described by older age of the patients.

Also FDA looked at 14 additional studies about Prilosec and Nexium and found that those people who took heartburn pill versus dummy pill had lower chance of heart related problems.

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