Nexium vs. Prilosec

Today’s consumer is so much more knowledgeable than ever before because information is readily available, at the click of a mouse, on the Internet. This is especially true when researching medications such as Nexium vs. Prilosec. In years gone by, it was necessary to find a PDR (Physician’s Desk Reference) but that information was often beyond the scope of our understanding.

The following information on both Nexium and Prilosec is in laymen’s terms to help you to better understand what the two medications are if you are suffering from any of the conditions for which they are prescribed. This information is not meant to replace proper medical advice and it is always recommended that you consult with your own doctor prior to taking any medications for the first time.

Nexium vs. Prilosec – What Are They?

Both Nexium and Prilosec are in a class of drugs called ‘proton pump inhibitors’ which work by decreasing the amount of acid produced in the stomach. They are both commonly prescribed for conditions such as GERD (gastroesophageal reflux disease), for the treatment and prevention of stomach ulcers, and other conditions such as Zollinger-Ellison syndrome. Usually when you are comparing Nexium vs. Prilosec it would be for a more serious condition as mentioned above.

Neither medication is recommended for incidental heartburn as they do not work immediately to reduce acid indigestion. In fact, it can take anywhere from one to four days for either medication to become effective, at which point the entire course needs to be carried out. You should not stop taking either medication until all doses have been taken.

Nexium vs. Prilosec – How They Are Sold

One of the first questions which many people have is in regards to how these two medications are sold. When considering Nexium vs. Prilosec, it is important to know that only one of these medications is currently available OTC. Only Prilosec is available over-the-counter while stronger Prilosec dosages are available still in prescription formulations.

The generic name for Prilosec is Omeprazole and the pharmaceutical name for Nexium is Esomeprazole. As you can see by their names, they are closely related and simply have a slightly different molecular structure. While you would need a prescription, as mentioned, for Nexium, you can readily purchase Prilosec OTC at most pharmacies and many supermarkets in the United States.

Nexium vs. Prilosec – How They Are Taken

Sometimes the most important ‘feature’ of a medication is how it is administered. For example, some people have trouble taking pills so they need liquid formulations while other times consumers don’t like to ‘taste’ the medicine so they prefer to take capsules or pills. When comparing how Nexium vs. Prilosec compare in regards to how they are taken, there is no difference.

Both Nexium and Prilosec are available in delayed release capsules and delayed release granules to be mixed with water. Both medications can also be fed through a feeding tube if necessary. Although you would need to follow the directions provided by your doctor/pharmacist, it is recommended that both medications be taken about an hour before eating.

Nexium vs. Prilosec Side Effects and Adverse Reactions

Although there are really few side effects being reported in regards to any of the proton pump inhibitors, it is possible to experience nausea, diarrhea, headaches or stomach pain/discomfort when taking either medication. This is perhaps the number one reason why many people compare Nexium vs. Prilosec; they just want to know if either medication will cause more or less discomfort and if either drug has more side effects than the other. Since both are proton pump inhibitors, it is likely they will both have closely related side effects if you are allergic to this class of pharmaceuticals.

As far as adverse reactions go, it is always advisable to talk to your doctor and/or pharmacist before taking any medications, especially if you are currently taking any medications, vitamins or natural supplements whatsoever. However, it is known that proton pump inhibitors, all of them, can react negatively with blood thinners such as Coumadin, diuretics, Cilostazol, Digoxin, Clopidogrel, Diazepam, Saquinavir and Iron. Since this is by no means a comprehensive list, always talk to your doctor before taking either Nexium or Prilosec if you are currently taking any medications.

Important Information and Special Precautions

When taking any medication, it is important to know if there are any special precautions which should be understood and observed. Again, when comparing Nexium vs. Prilosec, it is imperative that you understand that they are both in a class of pharmaceuticals called proton pump inhibitors. Neither medication is intended to work immediately nor should they be discontinued before all doses have been taken.

Also, it is important to understand that these medications do not work immediately – they are not intended to do so. This is perhaps the number one reason why a person may be tempted to take more than the recommended or prescribed dosage. They work by inhibiting the amount of acid produced in the stomach and this is a biological process which takes time to correct.

If, for any reason, you have taken too much of either Nexium or Prilosec watch for symptoms such as lightheadedness, dizziness, nausea and in extreme cases, a tightness or closing of the throat. It is recommended that you either call your local fire rescue at 911 if you feel as though you will lose consciousness or if you have found someone unconscious due to an accidental overdose. Otherwise, call your physician or pharmacist immediately if you feel you have taken too much of either drug.

Also, if you have missed a dose of either Nexium or Prilosec, take it immediately unless it is too close to the next dose. This is where you would need to use some good old fashioned common sense. For example, if you are taking a proton pump inhibitor once a day in the evening before your dinner and you discover at lunchtime that you forgot yesterday’s pill, it would be foolish to take it then as the next dose is only a couple of hours away. However, if you remember at bedtime that you forgot to take your medication, it is fine to take it then but you would most likely need a light snack afterwards as it is recommended to take both medications an hour before eating.

Finally, if you have any other medical conditions or diseases whatsoever, you should discuss with your physician the advisability of taking either medication. Anyone with liver or kidney dysfunction is at particular risk. Pregnant or lactating women should not take any medications without first consulting with their doctors and anyone with calcium deficiencies should likewise use caution. Proton pump inhibitors are known to make some people more susceptible to fractures, especially of the wrists, ankles, hips and back.

Consumer Reviews

When comparing Nexium vs. Prilosec many people also like to know what others are saying about the products. Since Nexium is only available in prescription form, you will only find consumer reviews from individuals who were prescribed Nexium for very specific conditions or diseases. For this reason, keep in mind that a medical doctor or medical professional made a diagnosis and is treating it accordingly. In light of this, Nexium is getting rave reviews coming in at 9 out of 10.

On the other hand, Prilosec is available over-the-counter so that many people take it after self-diagnosing the problems they are experiencing. Consumers report that Prilosec didn’t relieve their acid indigestion, acid reflux or heartburn as it is sometimes called, and they gave Prilosec a review based on something it was never intended to do. That can be a real problem when it comes to OTC medications because consumers don’t take the time to read what the medication can and can’t do. For those consumers who either understood how proton pump inhibitors are meant to work or were prescribed Prilosec for a very specific condition such as GERD, the reviews are equally as positive as those pertaining to Nexium.

Summary

To be fair, unless you are comparing prescription strength Nexium vs. Prilosec there is not accurate way to determine which is the better medication. Since only Prilosec is available OTC in the United States at this point in time, it would be impossible to do a complete assessment. However, since they are both closely related in the category of proton pump inhibitors with a slightly different molecular structure, it might be safe to say that either one could do the job treating the above mentioned conditions for which they were intended.

Keep in mind that neither medication is intended for the immediate relief of excess acid nor should either medication be discontinued before the entire course is complete. Also, unless you have been previously diagnosed for a specific condition that will respond to a proton pump inhibitor, it is not suggested that you take either medication without first consulting with your doctor. When comparing Nexium vs. Prilosec, the main difference is in how they are sold, prescription or OTC. After that, they are quite similar all the way around.

Omeprazole Information

Whenever a doctor prescribes a medication he or she has the option to check off a box that tells the pharmacist whether or not to fill the prescription with a generic drug if it is available. This could be the case with Omeprazole since it is marketed under a few different brand names. If your doctor wrote a prescription for Prilosec, Omesec or Losec and you find that it says Omeprazole, don’t worry as it is the same drug. It is simply the less expensive generic form.

What Is Omeprazole?

If you have been to the doctor and were given a prescription for omeprazole then you were probably given a diagnosis along with it! Actually, omeprazole is currently the treatment of choice for such conditions and illnesses as GERD, gastroesophageal reflux disease. It is also commonly prescribed for any conditions in which there is an overabundance of acid being produced by the stomach as would be the case if you had Zollinger-Ellison syndrome.

Some of the diagnoses for which omeprazole is prescribed would include ulcers which can be extremely painful sores in the lining of either the intestines or the stomach. Other times it is used to prevent ulcers from returning as they often do when H. pylori is present. In this case, omeprazole is prescribed along with an antibiotic. All of the above however are in terms of the prescription form of the generic pharmaceutical, omeprazole.

There is also an over-the-counter (OTC) formulation of omeprazole as well, such as Prilosec OTC. While Prilosec can be a bit costly, there are generic forms of the same medication which can have exactly the same results. Keep in mind that OTC omeprazole is not as strong as the prescription strength which is why it can be used to treat frequent bouts of heartburn or acid reflux.

Omeprazole is what is known as a photon pump inhibitor which is a type of medication that decreases the amount of acid which can be produced in the stomach. The prescription strength is not meant to treat heartburn or mild cases of acid reflux but the OTC product can be used if heartburn is a problem at least a few times weekly on a regular basis.

How Is Omeprazole Taken?

When you are prescribed omeprazole, your doctor will either write the script for delayed-release capsules or you could be given delayed-release granules that come in individual packets. Both forms should be taken approximately 60 minutes before meals. Most often you will be told to take the omeprazole dosage once daily, but there may be times when the doctor will increase that dosage to twice daily, especially when other medications are being taken concurrently.

Nonprescription strength omeprazole is usually taken once daily, again an hour before meals. However, there are a few points to consider when taking OTC omeprazole. The first thing is that it should not be taken if you are looking for immediate relief of acid reflux or heartburn as it can take anywhere from one to four days to work. Secondly, if you have trouble swallowing the capsules you can open the capsule and mix the contents with a small amount of applesauce. However, make sure that you do not chew the applesauce/omeprazole mix as the medication is delayed-release and long lasting. Simply follow with a few sips of water to make sure the mixture makes it through to your stomach.

Prescription granule packets can be mixed in the same way or can be added to a bit of apple juice. In either case, make sure not to chew or crush the delayed-release granules and also follow with water to make sure the entire dosage reaches your stomach. Always make sure to follow the instructions on the medicine bottle or packet unless different directions have been provided by your doctor. Also, take all of the omeprazole oral medication until the entire course is complete.

Potential Side Effects, Adverse Reactions

There are few side effects which have been associated with omeprazole, either in clinical trials or in patients who have used it over the years. Nonetheless, as with any medication, omeprazole drug interaction side effects are always a possibility as are reactions in patients who are sensitive to this category of pharmaceuticals. Tell your physician if you are allergic to any of the following drugs, which include:

• Dexlansoprazole
• Esomeprazole
• Pantoprazole
• Lansoprazole
• Rabeprazole

Also, you should advise your physician or pharmacist if you are taking any medications whatsoever including vitamins, minerals and other natural supplements. This is because any pharmaceutical has the potential to interact with other drugs. Of special concern are:

• Ampicillin
• Anticoagulants
• Benzodiazepines
• Cilostazol
• Clopidogrel
• Cyclosporine
• Ketoconazole
• Neflinavir
• Diuretics
• Digoxin
• Disulfiram

And the list goes on. These are just a few of the drugs which potentially can have an adverse reaction when taking omeprazole so it is vital to discuss any and all meds or supplements you are currently taking or have taken in the recent past.

Special Precautions When Taking Omeprazole

Many people have the unfortunate habit of discontinuing medication when they begin to feel better. One of the special precautions when taking omeprazole 40mg capsules or omeprazole 20 mg capsules is that they feel better, so they figure the condition is ‘fixed.’ This is not the case so it is important to continue taking the entire prescription until it is finished.

The same holds true for OTC omeprazole drug class medications as they are all varying strengths of the same proton pump inhibitors. It takes a good few days before the effects begin to be felt but the purpose of this medication is to keep the stomach from producing excess acid which takes time. Yes, in the beginning the acid will be minimized, but for the full impact of the medication the entire course must be completed.

Also, you should never take this medication for longer than two weeks at a time within a four month timeframe. In other words, take the entire course and then wait four months before taking it again. This holds true for both the prescription strength as well as the OTC strength and remember to tell any new doctors that you have already taken omeprazole if he or she tries to prescribe it before the four month time period is over.

A few other precautions to be aware of is that your doctor should be told if you have been experiencing repeated bouts of heartburn which has lasted longer than three months and if you have experienced any unusual physical symptoms with that heartburn such as dizziness, sweating or lightheadedness along with chest pain radiating down your back or arms. Many heart attacks could have been prevented because they were thought to be a simple case of heartburn.

It should go without saying that if you are pregnant or nursing you should consult with your doctor before taking omeprazole as should anyone of Asian descent or those with low blood levels of magnesium or liver disease. (It is unclear why those of Asian descent may have a problem as the manufacturer doesn’t elucidate on that point. Some individuals taking omeprazole may also be susceptible to more easily breaking bones in their wrists, spine and hips and those who have taken the drug for an extended period may also experience ulcers in the lining of the stomach.

Important Information Regarding Omeprazole

Many people have wondered if it is possible to overdose on omeprazole or even how to recognize the symptoms. Generally, if you find that you are inordinately dizzy, drowsy, nauseous or confused, you should seek medical intervention. If you come into a room where someone has passed out then it is imperative that you call 911 immediately.

Again, it is essential that you understand just how important it is to take the entire course of this medicine as it takes several days to begin working and for the longest lasting effects it will take much longer. It is also extremely important to remember that you cannot take it more often than once every four months. If you have any questions whatsoever, contact your doctor or pharmacist before taking this medication.

Summary

Omeprazole is the most prescribed medication around the world for such conditions as GERD and it has had wonderful results with few major side effects. Keeping in mind that no two people ever react the same to any given medicine, there is always the potential for side effects and/or adverse reactions.

Finally, this information is provided for educational purposes only and is not intended to replace a proper medical diagnosis with the appropriate treatment. It is always recommended that you seek medical advice from a licensed medical professional before taking any medications for the first time, even if they are generally recognized as safe (GRAS). It is never advisable to self diagnose because you may be misreading the symptoms. Keep all medications out of the reach of small children and in an airtight container.

Prilosec Information

Even though Prilosec is now sold over-the-counter (OTC), it is always recommended that consumers know what it is and what it can do for them before self medicating. Simply because it is located on a pharmacy shelf next to antacids and other medications for indigestion doesn’t necessarily mean this would be the preferred treatment for what you are suffering from. The following information is not intended to diagnose or prescribe treatment, rather it is intended to provide a basic understanding of what Prilosec is, its intended uses and other facts which may prove to be helpful. Consumers should always seek a professional medical diagnosis before beginning any medications, especially for the first time.

What Is Prilosec?

The chemical (pharmaceutical) name for Prilosec is omeprazole which was first released in 1989 as a prescription drug for peptic ulcers, dyspepsia, laryngopharyngeal reflux, gastroesophageal reflux disease (commonly referred to as GERD) and Zollinger-Ellison syndrome. Today Prilosec is the most prescribed medication for GERD on a global level although it is still commonly prescribed for the previously mentioned conditions and other less common conditions.

Although the average layperson wouldn’t need to know, or even understand, Prilosec is in a class of medications known as proton pump inhibitors. Basically, this means that it is used to treat illnesses or conditions which have been brought about by excess acid in the stomach. Sometimes it is prescribed for its ability to heal a condition called erosive esophagitis and there are times when physicians prescribe it in combination with antibiotics for ulcers which are the result of infections caused by H. pylori.

This medication is still available in prescription strength but is now available in the United States and some other countries around the world in an OTC strength formulation. Prilosec should not be taken for common conditions such as heartburn or acid indigestion because it does not promote immediate relief for those conditions.

How Is Prilosec Taken?

There are several ways in which Prilosec can be taken orally which of course include taking the capsule or pill whole as directed, generally one hour before breakfast. However, there are other ways in which Prilosec can be administered orally which would include the powder oral suspension formulation and methods of taking capsules for individuals who have trouble swallowing. In this case the person may wish to use a small bit of applesauce, usually a tablespoon, in a small bowl. Break open the time-release capsule and mix it well with the applesauce. Be sure not to chew when swallowing the mixture as the little granules are time released and never store the mixture. Take it immediately.

Delayed release tablets, prescription or OTC, are never to be chewed. Swallow them whole with a glass of water as per the directions on the OTC box or as prescribed by your physician. The powder form should be mixed with water, usually one teaspoonful for the 5mg dose and a tablespoon for the 10 mg dose. In either case, place the water in a small medicine cup and add the powder. Stir it well and wait a few minutes until the mixture thickens. Mix it again and immediately drink it down. Never let the mixture stand longer than 30 minutes. If for some reason you are unable to take your medication within that time, throw it out and start again. The powder can also be fed through a feeding tube if necessary following instructions by the doctor.

Potential Side Effects and Adverse Reactions

As with any medication, there is always the potential for side effects and/or adverse reactions. If you experience any of the following side effects, especially over a prolonged period, you should consult with your physician. Potential side effects include irregular bowel movements such as diarrhea or constipation, stomach pain, gas, nausea or vomiting and some people have experienced fevers and/or headaches.

Most often symptoms are not severe, but in some rare instance they could be. Of concern would be anyone presenting with a rash, hives or itching as this could be an allergic reaction. Any swelling of the face, neck, throat, lips, tongue or extremities (i.e. hands, ankles) should be immediately reported to your doctor. Hoarseness, dizziness, lightheadedness, irregular heartbeats, uncontrollable shaking, muscle spasms or seizures should also be immediately reported.

Special Precautions When Taking Prilosec

One thing to be aware of when taking Prilosec is that proton pump inhibitors seem to make people more susceptible to breaking bones such as hips, wrists and even their spine than those who do not take the compound. This is most common in those over the age of 50 and in patients who take high doses. There is also the risk of weakening the stomach lining if taken over extended periods of time.

Prilosec is not intended for immediate relief which is why it is contraindicated in relieving the symptoms of heartburn as it could take anywhere from one to four days before the effects are felt. Also, this medication is not meant to be taken over extended periods of time. OTC Prilosec should only be taken for 14 days at the longest and you should not follow the recommended OTC course more often than once in a four month period unless prescribed to do so by your physician.

Symptoms of Overdose and Emergency Procedures

Keep in mind that Prilosec is not a simple antacid and it is possible to overdose. While it may seem highly unlikely that someone would take more than prescribed or recommended on the OTC packaging, it has been known to happen. The pain and burning which accompanies conditions like GERD or peptic ulcers can be almost unbearable which is why people have been known to try to take extra medication. Even if there were no possibility of overdosing, it would be of no benefit anyway as it takes several days to be effective.

Symptoms of overdosing could include, but are not limited to, blurred vision, dizziness, irregular (rapid) heartbeats, vomiting or nausea, feeling flushed, dry mouth and headaches. If you suspect that you may have inadvertently taken too much of your Prilosec, you could call the National Poison Control Hotline at 1-800-222-1222 or your local emergency 911. If you find another person unconscious it is best to immediately call 911 since calling the national hotline will just unnecessarily delay medical intervention. They will only patch you through to your local fire/rescue which can delay responders by many minutes.

Important Information Regarding Prilosec

Before taking any medications whatsoever, including Prilosec, it is suggested that you discuss with your own doctor what medications or supplements you are currently taking. This includes OTC medications, vitamins, minerals and any prescription pharmaceuticals prescribed by other physicians. You would also want to discuss any allergies you may have to other medications and also if you have taken a course of Prilosec within the past few months. Remember, even a course of OTC Prilosec is only taken once in a four month period.

Your doctor may request a series of diagnostic tests before prescribing any medications so it is important to keep all appointments. Prilosec is most often prescribed for GERD which can have long-lasting ramifications if not treated timely. Never let another person take your prescription medication and also discuss any other illnesses you may have with your doctor. Pregnant women should always let their doctor know they are pregnant before taking any medications as well.

Consumer Reviews

When reading consumer reviews around the internet, it is apparent that many of them either didn’t read the directions or chose to take matters into their own hands anyway. One person commented that Prilosec was ineffective at treating heartburn so he/she had to take it repeatedly during the day. Either this was not Prilosec being taken or, as mentioned, the packaging wasn’t read. Prilosec is not for immediate relief of heartburn!

Some users found that it made them a bit drowsy but were happy with the relief it provided them while others found that it gave them mood swings or made them edgy. These, however are a rare few instances as most of the people who have taken Prilosec rate it at least 8 out of 10 for efficiency and would highly recommend it to others. OTC Prilosec can be a bit pricey at a local pharmacy, but it is possible to find deals online with a bit of searching. This is especially helpful if the online vendor provides free shipping.

Summary

If used as directed and for the conditions for which it was meant to be used, Prilosec is among the most effective medications of its type. It may be a bit costly, but no more so than other pharmaceuticals in this classification and there may be generic names under which the same medication is manufactured which could be less expensive. It is the number one pharmaceutical treatment of choice for GERD and as it has been on the market for more than two decades it can be classified as GRAS, generally recognized as safe. However, the bottom line is to always consult with your physician before taking any medications for the first time, even in non-prescription strengths.